Tsunade, as well as her former teammates Jiraiya and Orochimaru, is a former student of the Third Hokage. She is also the granddaughter of the First Hokage, and so many characters in the series refer to her with the Japanese honorific "hime" (meaning "princess"). Despite her connections to past Hokage, Tsunade hates the position when she is first introduced. After her brother and boyfriend died in pursuit of their dreams to become Hokage, she lost faith in the title and the concept of dreams.
